A study published in Cardiovascular Psychiatry and Neurology Journal noted a link between a leaky brain and depression. Another study published in the 2017 edition of Neurology Journal showed those with high levels of neurological inflammation showed correspondingly higher levels of depression and anxietyLearn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your free Weight Loss Food List, the “Eat More, Lose More” Weight oss Plan, and the “Slim in 6” Cheat Shee

the potential effect on your mind

As you might expect, this brain syndrome also has a considerable effect on the mind. According to a study by the University of Cambridge, there is little doubt neurological inflammation plays a large role in cognitive disorders.

What are cognitive disorders?

A cognitive disorder can be as “minor” as occasional forgetfulness or brain fog and as major as Alzheimer’s and Parkinson’s disease. Dementia is also a cognitive disorder. So, the memory problems many people consider as just normal age-related issues may actually be caused by leaky brain syndrome and neurological inflammation.

Speaking of Alzheimer’s, a 2015 study published in the Journal of Neuroscience openly refers to neurological inflammation as being a well-known coexisting factor of Alzheimer’s. An estimated 5.5 million people in the U.S. suffer from Alzheimer’s, a progressively incapacitating disease that is fatal. It has no known cure. If a poorly optimized brain turns out to be the cause of Alzheimer’s, just think of the numbers of lives that could be saved from this dreadful disease. After all, there are cures for it (as you’ll learn shortly.)

Brain gut hormone axis involved?

Studies show leaky brain syndrome can also cause a slowed metabolism and weight gain. The reasons how and why this can happen is not that difficult to understand. You see, the brain has always been in charge of the metabolism.

More and more functional medicine patients are becoming familiar with the notorious leaky gut syndrome. If you have leaky gut, chances are you have leaky brain too as similar mechanisms cause it.

The hypothalamus in your brain is in charge of balancing calories in and calories out.  The hormones leptin and insulin regulate the hypothalamus. They send signals to the hypothalamus letting it know how much fat you have and how much fat you need to burn or store. If everything is working correctly, when your calorie intake increases, you will simply burn more calories. In this way, you’ll never become too heavy or too thin. In other words, your brain and hormones balance your weight at  your setpoint weight


But when this syndrome causes neurological inflammation, these signals stop working. The hypothalamus either no longer receives these signals or it cannot read them correctly. The result is that it gives you more fat. Your brain and hormones now work to hold on to extra weight, and it doesn’t matter how little you eat or how hard you workout at the gym. If you do lose weight by cutting calories, you’ll gain all the weight back as soon as you go off that diet.

In other words, cutting-edge research proves neurological inflammation raises setpoint weight, making it nearly impossible to lose those extra pounds until you heal the inflammation.

A 2016 study in The Journal of Nutritional Biochemistry boldly declares neurological inflammation to be a likely cause of hormonal dysregulation leading to obesity. That’s not the only study linking neurological inflammation to an elevated setpoint weight and consequent weight gain.


Studies even show leaky brains affect physical health. Specifically, the neurological inflammation it causes leads to high blood pressure and insulin resistance that increases the risk for disease.

In fact, several studies have demonstrated that neurological inflammation leads to insulin resistance and other symptoms of metabolic syndrome, all of which increase the risk of heart disease, type 2 diabetes, and kidney disease. (Metabolic syndrome has just recently emerged as a valid risk factor for kidney disease.)

But leaky brain does not just cause symptoms of metabolic syndrome. A review published in the Medical Hypotheses Journal found that leaky brain may contribute to chronic fatigue syndrome, a condition that causes extreme tiredness.

What is a leaking brain caused from mainly?

Many things contribute to leaky brain syndrome, but probably the main cause is the Standard American Diet.

Regularly eating refined sugars, starchy carbs, and heavily processed foods harm the integrity of the blood-brain barrier, causing it to become “leaky.” Sugars and refined carbs also cause systemic inflammation, which itself can cause the tight junctions to become more permeable, allowing dangerous substances into the brain’s fragile environment.